Lorenz S. Neuwirth

neuwirthl's picture

Job title: 

Assistant Professor
Biopsychology, Developmental Behavioral Neuroscience & Neuropsychology

Phone: 

(516)628-5048

Fax: 

(516)876-8432

E-mail: 

neuwirthl@oldwestbury.edu

Building: 

New Academic Building

Room: 

2059

Office hours: 

  • Fall 2019:
    Tuesdays and Thursdays
    5:30pm-7:00pm & 10:30pm-11:00pm

Courses taught: 

  • PY3010 Research, Design, & Analysis I
  • PY3120 Research Methods II: Basic Statistics for Psychologists
  • PY3420 Learning and Motivation
  • PY3610 Brain & Behavior
  • PY3620 Drugs & Behavior
  • PY4010 History of Psychology
  • PY4100 Research Methods III: Advanced Research Skills
  • PY4401 Developmental Neuropathology
  • PY4402 Neuropsychopharmacology
  • PY5404 Environmental Neuroplasticity
  • PY5610 Research Perspectives in Neuropsychology
  • PY9990 Independent Study in Psychology: Critical & Analytical Writing Skills
  • PY9990 Independent Study in Psychology: Neuroscience Laboratory Skills

Education: 

Degrees:

  • 2013-2015 Postdoc Neurotoxicology, Neurodegenerative Disorders and Molecular Epigenetics - Thomas Jefferson University, Philadelphia, PA
  • 2014 Ph.D. Biology/Neuroscience - The CUNY Graduate Center, New York, NY
  • 2012 M.Phil. Biology/Neuroscience - The CUNY Graduate Center, New York, NY
  • 2008 M.S. Neuroscience, Mental Retardation and Developmental Disabilities - The College of Staten Island (CUNY), Staten Island, NY
  • 2005 B.A. Psychology - The College of Staten Island (CUNY), Staten Island, NY

Certifications:

  • 2015 Certification in Cognitive Disorders, Frontal Lobe Organization, Brain Lateralization, & Executive Functions - Luria Neuroscience Institute, New York, NY
  • 2006 Certification in Disability Studies - The School of Professional Studies at The CUNY Graduate Center, New York, NY

Awards:

  • 2019 The Brenda A. Milner Award for Outstanding Paper in the Field of Behavioral Neuroscience - Presented at the 2019 American Psychological Association (APA) 127th Annual Meeting, by the APA Division 6: Society for Behavioral Neuroscience and Comparative Psychology (SBNCP) (Chicago, IL)
  • 2018 The Faculty for Undergraduate Neuroscience (FUN) Carol Ann Paul Educator of the Year Award - Presented at the 2018 Society For Neuroscience (SFN) 58th Annual Meeting (San Diego, CA)

Research interests: 

Dr. Neuwirth’s research focuses on developmental behavioral neurotoxicology (how the brain develops), molecular epigenetics (how environments and genes interact with each other), neurodegenerative diseases (how brain processes and activity reduce as a consequence of aging) with emphasis on metal neurotoxins such as lead (Pb) and other environmental contaminants. Moreover, he investigates the effects of lead poisoning and other environmental contaminants on early brain development and later life cognitive and behavioral consequences with intent to find drug therapies for ameliorating these persistent social problems. He has interest in developing and designing new behavioral technology that can measure very sensitive aspects of cognition and other learning and memory processes. In addition to understanding the relationship between environmental-gene interactions that negatively influence brain development, his research also investigates the neurobehavioral characterization of Autism in Fragile X rodent models with focus on treating cognitive deficits and social-emotional disturbances. Dr. Neuwirth has over 12 years of training in both applied and basic research science integrating biology and psychology which translates into understanding the development of the frontal cortex, hippocampus, and the amygdala and how early brain disruption results in lifelong intellectual and social-emotional disabilities that persist as economic and public health concerns.

Select publications & presentations: 

Publications:

[25] Neuwirth, L.S., Kim, Y.J., Barrera, E.D., Jo, C., Chrisphonte, J.M., Hameed, N., Rubi, S., Dacius Jr., T.F., Skeen, J.C., Bonitto, J.R., Khairi, E., Iqbal, A., Ahmed, I., Masood, S., Tranquille, B. & Thiruverkadu, V. (2019). Early neurodevelopmental exposure to low lead levels induces fronto-executive dysfunctions that are recovered by taurine co-treatment in the rat attention set-shift test: Implications for taurine as a psychopharmacotherapy against neurotoxicants. In J. Hu, F. Piao, S.W. Schaffer, A. El Idrissi & J.Y. Wu (Eds.), Taurine 11, Advances in Experimental Medicine and Biology, Vol. 1155: 821-846. https://doi.org/10.1007/978-981-13-8023-5_70

[24] Neuwirth, L.S., Emenike, B.U., Barrera, E.D., Hameed, N., Rubi, S., Dacius Jr., T.F., Skeen, J.C., Bonitto, J.R., Khairi, E., Iqbal, A., Ahmed, I., Jose, T.J. Lynch, K.P., Khan, M., Alvira, A.L., Mathew, N., Kaur, S., Masood, S., Tranquilee, B. & Thiruverkadu, V. (2019). Assessing the anxiolytic properties of taurine-derived compounds in rats following developmental lead exposure: A neurodevelopmental and behavioral pharmacological pilot study. In J. Hu, F. Piao, S.W. Schaffer, A. El Idrissi & J.Y. Wu (Eds.), Taurine 11, Advances in Experimental Medicine and Biology, Vol. 1155: 801-819. https://doi.org/10.1007/978-981-13-8023-5_69

[23] Budylin, T., Guariglia, S.R., Duran, L.I., Behring, B.M., Shaikh, Z., Neuwirth, L.S. & Banerjee, P. (2019). Ultrasonic Vocalization Sex Differences in 5-HT1A-R Deficient Mouse Pups: Predictive Phenotypes Associated with Later-life Anxiety-like Behaviors. Behavioural Brain Research, 375, 112062 https://doi.org/10.1016/j.bbr.2019.112062

[22] Neuwirth, L.S., Masood, S., Anderson, D.W. & Schneider, J.S. (2019). The attention set-shifting test is sensitive for revealing sex-based impairments in executive functions following developmental lead exposure in rats. Behavioural Brain Research, 366, 126-134. https://doi.org/10.1016/j.bbr.2019.03.022

[21] Neuwirth, L.S., Ebrahimi, A., Mukherji, B.R. & Park, L. (2019). Addressing diverse college students and interdisciplinary learning experiences through online virtual laboratory instruction: A theoretical approach to error-based learning in biopsychology. In Information Resources Management Association (Ed.), Virtual reality in education: Breakthroughs in research and practice: IGI Global 511-531. https://www.igi-global.com/chapter/addressing-diverse-college-students-and-interdisciplinary-learning-experiences-through-online-virtual-laboratory-instruction/195070

[20] Neuwirth, L.S. (2019). Basic Psychopharmacology. In S.M. Evans (Ed.), American Psychological Association Handbook of Psychopharmacology. pp. 41-59. Washington, D.C.: American Psychological Association. http://dx.doi.org/10.1037/0000133-003

[19] Neuwirth, L.S. (2018). Resurgent lead poisoning and renewed public attention towards environmental social justice issues: A review of current efforts and call to revitalize primary and secondary lead poisoning prevention for pregnant women, lactating mothers, and children within the U.S. International Journal of Occupational and Environmental Health: 1-15. https://doi.org/10.1080/10773525.2018.1507291

[18] Neuwirth, L.S., Phillips, G.R. & El Idrissi, A. (2018). Perinatal Pb2+ exposure alters the expression of genes related to the neurodevelopmental GABA-shift in postnatal rats. Journal of Biomedical Science, 25(45), 1-11. https://doi.org/10.1186/s12929-018-0450-4

[17] Neuwirth, L.S., Dacius, Jr. T.F. & Mukherji, B. Runi (2018). Teaching neuroanatomy through a historical context. The Journal for Undergraduate Neuroscience Education (JUNE), 16(2), E26-E31. http://www.funjournal.org/wp-content/uploads/2018/04/june-16-e26.pdf

[16] Tait, D.S., Bowman, E.M., Neuwirth, L.S. & Brown, V.J. (2018). Assessment of intradimensional/extradimensional attentional set-shifting in rats. Neuroscience & Biobehavioral Reviews, 89, 72-84. https://doi.org/10.1016/j.neubiorev.2018.02.013

[15] Neuwirth, L.S., Ebrahimi, A., Mukherji, B.R. & Park, L. (2018). Addressing diverse college students and interdisciplinary learning experiences through online virtual laboratory instruction: A theoretical approach to error-based learning in biopsychology. In A. Ursyn (Ed.), Visual Approaches to Cognitive Education with Technology Integration: 283-303. https://www.igi-global.com/chapter/addressing-diverse-college-students-and-interdisciplinary-learning-experiences-through-online-virtual-laboratory-instruction/195070

[14] Neuwirth, L.S., Volpe, N.P., Corwin, C., Ng, S., Madan, N., Ferraro, A.M., Furman, Y. & El Idrissi, A. (2017). Taurine recovery of learning deficits induced by developmental Pb2+ exposure. In D.H. Lee, S. Shaffer, E. Park & H.W. Kim (Eds.), Taurine 10, Advances in Experimental Medicine and Biology, Vol. 975: 39-55. https://doi.org/10.1007/978-94-024-1079-2_4

[13] Mukherji, B.R., Neuwirth, L.S. & Limonic, L. (2017). Making the case for real diversity: Redefining underrepresented minority students in public universities. Sage Open, Special Diversity Edition. (Apr.-June): 1-10. https://doi.org/10.1177/2158244017707796

[12] Gökhan, N., Neuwirth, L.S. & Meehan, E.F. (2017). The Effects of low dose MK-801 administration on NMDAR dependent executive functions in pigeons. Physiology and Behavior, 173: 243-251. https://doi.org/10.1016/j.physbeh.2017.02.009

[11] Neuwirth, L.S., Volpe, N.P., Ng, S., Marsillo, A., Corwin, C., Madan, N., Ferraro, A.M. & El Idrissi, A. (2015). Taurine recovers mice emotional learning and memory disruptions associated with Fragile X Syndrome in context fear and auditory cued-conditioning. In. J. Marcinkiewicz and S.W. Schaffer (Eds.), Taurine 9; Advances in Experimental Medicine and Biology, Vol. 803: 425-438. New York, NY: Springer Press. https://doi.org/10.1007/978-3-319-15126-7_33

[10] Neuwirth, L.S. (2014). The characterization of Pb2+ toxicity in rat neural development: An assessment of Pb2+ effects on the GABA shift in neural networks and implications for learning and memory disruption. UMI Proquest Dissertations & Theses 3612469. DAI/B 75-06(E), Apr 2014.

[9] Neuwirth, L.S., Volpe, N.P. & El Idrissi, A. (2013). Taurine effects on emotional learning and memory in aged mice: Neurochemical alterations and differentiation in auditory cued fear and context conditioning. In A. El Idrissi and W. L’Amoreaux (Eds.), Taurine 8: Physiological Roles and Mechanisms of Action, Advances in Experimental Medicine and Biology, Vol. 775: 195-214. New York, NY: Springer Press. https://doi.org/10.1007/978-1-4614-6130-2_17

[8] Shen, C.H., Lempert, E., Butt, I., Neuwirth, L.S., Yan, X. & El Idrissi, A. (2013). Changes in gene expression at inhibitory synapses in response to taurine treatment. In A. El Idrissi and W. L’Amoreaux (Eds.), Taurine 8: Physiological Roles and Mechanisms of Action, Advances in Experimental Medicine and Biology, Vol. 775: 187-194, New York, NY: Springer Press. https://doi.org/10.1007/978-1-4614-6130-2_16

[7] Santora, A., Neuwirth, L.S., L’Amoreaux, W.J. & El Idrissi, A. (2013). The effects of chronic taurine supplementation on motor learning. In A. El Idrissi and W. L’Amoreaux (Eds.), Taurine 8: Physiological Roles and Mechanisms of Action, Advances in Experimental Medicine and Biology, Vol. 775: 177-185, New York, NY: Springer Press. https://doi.org/10.1007/978-1-4614-6130-2_15

[6] El Idrissi, A., Okeke, E., Yan, X. & Neuwirth, L.S. (2013). Taurine regulation of blood pressure and vasoactivity. In A. El Idrissi and W. L’Amoreaux (Eds.), Taurine 8: Physiological Roles and Mechanisms of Action, Advances in Experimental Medicine and Biology, Vol. 775: 407-425, New York, NY: Springer Press. https://doi.org/10.1007/978-1-4614-6130-2_31

[5] Purkayastha, S., Ford, J., Kanjilal, B., Diallo, S., Inigo, J., Neuwirth, L.S., El Idrissi, A., Ahmed, Z., Wieraszko, A. & Banerjee, P. (2012). Clozapine functions through the prefrontal cortex serotonin 1A receptor to heighten neuronal activity via calmodulin kinase II-NMDA receptor interactions. Journal of Neurochemistry, 120 (3): 396-407. https://doi.org/10.1111/j.1471-4159.2011.07565.x

[4] El Idrissi, A., Iskra, B. & Neuwirth, L.S. (2012). Neurobehavioral effects of taurine in fragile X syndrome. In A. El Idrissi and W. L’Amoreaux (Eds.), Taurine in health and disease. pp.293-328, Kerla, India: Transworld Research Network.

[3] El Idrissi, A., Okeke, E., Yan, X., Sidime, F. & Neuwirth, L.S. (2012). Taurine regulation of blood pressure and vascular resistance. In A. El Idrissi and W. J. L’Amoreaux (Eds.), Taurine in health and disease. pp.53-74, Kerla, India: Transworld Research Network.

[2] El Idrissi, A., Neuwirth, L.S. & L’Amoreaux, W.L. (2010). Taurine regulation of short term synaptic plasticity in Fragile X mice. Journal of Biomedical Sciences, 17 (Suppl 1): S15: 1-8. https://doi.org/10.1186/1423-0127-17-S1-S15

[1] El Idrissi, A., Boukarrou, L., Heany, W., Malliaros, G., Sangdee, C. & Neuwirth, L.S. (2009). Effects of taurine on anxiety-like and locomotor behavior of mice. In J. Azuma et al. (Eds.), Taurine 7: Taurine for the future healthcare, Advances in Experimental Medicine and Biology, Vol. 643: 207-215, New York, NY: Springer Press. https://doi.org/10.1007/978-0-387-75681-3_21

Presentations: 

[28] Neuwirth, L.S., Khairi, E., Cabañas, E., Ahmed, I., Skeen, J.C., Bonitto, J.R., Lynch, K.P., Joseph, J., Vasquez, M.A., Chrisphonte, J.M. & Kim, Y.J. (2019). The effects of developmental Pb-exposure on pilocarpine and kainic acid induced seizures. Poster presented at the 127th Annual American Psychological Association Conference Chicago, IL.

[27] Choe, A., Gillenwater, K., Hindi, B., Pilout, S., Kent, M., Neuwirth, L.S., Skeen, J.C., Lynch, K.P., Ahmed, I., Khairi, E., Bonitto, J.R., Cabañas, E., Vasquez, M.A., Cruz, G., Joseph, J. & Lambert, K.G. (2019). Neurobiological and anxiety-like behavioral outcomes of perinatal Pb-exposure in male and female rats. Poster presented at the 28th Annual International Behavioral Neuroscience Society Conference Cairns, Queensland, Australia.

[26] Hindi, B., Choe, A., Gillenwater, K., Pilout, S., Kent, M., Neuwirth, L.S., Skeen, J.C., Lynch, K.P., Ahmed, I., Khairi, E., Bonitto, J.R., Cabañas, E., Vasquez, M.A., Cruz, G., Joseph, J., Clarke, E., Ackloo, J. & Lambert, K.G. (2019). Effects of developmental lead exposure on sex-based neurobiological and anxiety-like behavioral outcomes in Long-Evans rats. Poster presented at the Central Virginia Chapter of Society for Neuroscience at the University of Virginia Charlottesville, VA.

[25] Neuwirth, L.S. (2019). Developmental lead poisoning impairs frontoexecutive functions in a sex-specific manner that is recovered by taurine co-treatment. Oral presentation at the University of Richmond Neuroscience & Psychology Seminar Series Richmond, VA.

[24] Neuwirth, L.S., Barrera, E., Rubi, S., Dacius Jr., T.F., Skeen, J., Hameed, N., Khairi, E., Bonitto, J.R., Iqbal, A., Lynch, K., Ahmed, I., Kaur, S. & Jose, T. J. (2018). Developmental lead exposure alters rodent maternal pup retrieval disrupting adolescent social play. Poster presented at the 126th annual American Psychological Association meeting San Francisco, CA.

[23] Neuwirth, L.S., Emenike, B.U., Barrera, E., Hameed, N., Rubi, S., Dacius Jr., T.F., Skeen, J., Bonitto, J.R., Khairi, E., Iqbal, A., Ahmed, I., Jose, T.J., Lynch, K., Khan, M., Allivira, A., Mathew, N., Kaur, S., Masood, S., Tranquille, B., & Thiruverkadu, V. (2018). Assessing the Anxiolytic Properties of Taurine-derived Compounds in Rats Exposed to Lead: A Neurodevelopmental and Behavioral Psychopharmacological Study . Poster presentation at the 21st Annual International Taurine meeting Conference, Shenyang and Dalian, China.

[22] Neuwirth, L.S., Kim, Y., Barrera, E., Jo, C., Chrisphonte, J.M., Hameed, N., Rubi, S., Dacius Jr., T.F., Skeen, J., Bonitto, J.R., Khairi, E., Iqbal, A., Ahmed, I., Masood, S., Tranquille, B., & Thiruverkadu, V. (2018). Early neurodevelopmental exposure to low lead levels induces frontoexecutive dysfunctions that are recovered by the co-treatment of taurine in the rat attention set-shift test: Implications for taurine as a psychopharmacotherapy against neurotoxicants. Oral presentation at the 21st Annual International Taurine meeting Conference, Shenyang and Dalian, China.

[21] Neuwirth, L.S., Kim, Y., Rubi, S.R., Kaur, S., Mathew, N., Masood, S., Tranquille, B., Thiruverkadu, V., Hameed, N., Jose, T.J., Jo, C., Dacius Jr., T.F., Bonitto, J.R. Skeen, J.C., Alvira, A., Khairi, E., & Iqbal, A. (2017). Low lead exposure alters cortical volume and neurotransmitter profiles in the rat. Poster presented at the annual Society for Neuroscience meeting Washington, DC.

[20] Neuwirth, L.S., Kim, Y., Jo, C., Dacius Jr., T.F., Jose, T.J., Hameed, N., & Bonitto, J.R. (2017). Low lead exposure alters cortical volume and neurotransmitter profiles in the rat. Poster presented at the 125th annual American Psychological Association meeting Washington, DC.

[19] Neuwirth, L.S., Volpe, N.P., Corwin, C., Ng, S., Madan, N., Ferraro, A.M., Furman, Y., & El Idrissi, A. (2016). Taurine recovery of learning deficits induced by developmental Pb2+ exposure. Oral presentation at the 20th Annual International Taurine meeting Conference, Seoul, Korea.

[18] Neuwirth, L.S. (2016). Lead Poisoned Minds and the Search for a Silver Lining: From Environmental Exposure to Frontoexecutive Dysfunctions Across the Lifespan. Oral presentation at the 2016 Annual Long Island Psychology Conference (LIPC), Old Westbury, NY.

[17] Neuwirth, L.S., Anderson, D.W., & Schneider, J.S. (2015). Low-level lead exposure differentially impairs cognitive flexibility in an attentional set shifting task dependent upon sex and development period of exposure. Poster presented at the 10th annual Postdoctoral Research Symposium meeting Thomas Jefferson University, Philadelphia, PA.

[16] Neuwirth, L.S., Masood, S., Anderson, D.W., & Schneider, J.S. (2015). Low-level lead exposure differentially impairs cognitive flexibility in an attentional set shifting task dependent upon sex and development period of exposure. Poster presented at the annual meeting of the Society for Neuroscience Conference, Chicago, IL.

[15] Neuwirth, L.S., Anderson, D.W., & Schneider, J.S. (2015). Low-level lead exposure differentially impairs attentional set shifting task performance depending on developmental period of exposure. Poster presented at the annual meeting of Society of Toxicology Conference, San Diego, CA.

[14] Neuwirth, L.S., Anderson, D.W., & Schneider, J.S. (2014). Low-level lead exposure Differentially impairs performance of an attentional set shifting task depending on development period of exposure. Poster presented at the annual meeting of the Society for Neuroscience Conference, Washington, DC.

[13] Neuwirth, L.S., Furman, Y., Madan, N., & El Idrissi, A. (2014). Effects of acute vs. chronic taurine treatment on context fear aversive conditioning in mice. Poster presented at the 19th Annual International Taurine meeting Conference, Krakow, Poland.

[12] Neuwirth, L.S., Volpe, N.P., Wieraszko, A., & El Idrissi, A. (2013). Chronic gestational lead exposure enhances spontaneous and inhibits stimulation-evoked release of glutamate analog, D-2, 3,-3H-aspartic acid from synaptosomes in early cortical and postnatal hippocampal development. Poster presented at the annual meeting of the Society for Neuroscience Conference, San Diego, CA.

[11] Neuwirth, L.S., Volpe, N., & El Idrissi, A. (2012). Effects of acute vs. chronic taurine treatment on context fear aversive conditioning in mice. Oral presentation at the 18th Annual International Taurine Meeting Conference, Marrakesh, Morocco.

[10] Santora, A., El Idrissi, A., Neuwirth, L.S., & L’Amoreaux, W. (2012). The effects of chronic taurine supplementation on motor learning. Poster presented at the 18th Annual International Taurine meeting Conference, Marrakesh, Morocco.

[9] Okeke, E., Neuwirth, L.S., & El Idrissi, A. (2012). The characterization of Pb2+ toxicity in the rat cardiovascular system: An assessment of Pb2+ induced pathophysiology. Poster presented at the 18th Annual International Taurine meeting Conference, Marrakesh, Morocco.

[8] Ng, S., Neuwirth, L.S., & El Idrissi, A. (2012). Effect of Nigella Sativa oil on GABAA-receptor mediated neurobehaviors in mice. Poster presented at the 18th Annual International Taurine meeting Conference, Marrakesh, Morocco.

[7] Neuwirth, L.S. & El Idrissi, A. (2012). Rat GABAergic neural developmental assessment of anxiety, fear potentiation, learning, memory, and pilocarpine induced temporal lobe epilepsy in the rat following chronic low-level lead exposure. Poster presented at the 18th Annual International Taurine meeting Conference, Marrakesh, Morocco.

[6] El Idrissi, A., L’Amoreaux, W., Neuwirth, L., Yan, X., & Sidime, F. (2010). Altered pancreatic development in the fragile x mouse: Functional consequences on glucose metabolism. Poster presented at the annual meeting of Neuroscience Conference, San Diego, CA.

[5] Neuwirth, L.S, Iskra, B., Hopkins, E., & El Idrissi, A. (2009). Evaluation of operant conditioning and reversal learning deficits in fragile x mice. Poster presented at the annual meeting of the Association for Behavior Analysis International Conference, Phoenix, AZ.

[4] Neuwirth, L.S, Iskra, B., L’Amoreaux, W., El Idrissi, A., & Lidsky, T.I. (2009). Taurine protects rats from locomotor disturbances induced by lead. Poster presented at the annual meeting of The College of Staten Island CUNY Urban University Conference, Staten Island, N.Y. and the annual meeting of The Society for Neuroscience Conference, Chicago, IL. 

[3] Neuwirth, L.S., Mahoney, L., & Cicero, F. (2008). Teaching an Adolescent with Autism How to Independently Brush His Teeth Through Analogue Instruction, Picture Sequencing and Differential Reinforcement. Poster presented at the annual meeting of the Association for Behavior Analysis International Conference, Chicago, IL.

[2] Zavyalova, E., Heany, W., El Idrissi, A., & Neuwirth, L.S. (2007). Effects of taurine on anxiolytic and locomotor behavior of mice. Poster presented at the annual meeting of the Society for Neuroscience Conference, San Diego, CA.

[1] Cicero, F., Hopkins, E., & Neuwirth, L.S. (2006). Functional assessment and treatment of operant bowel movement accidents in an adolescent with autism. Poster presented at the annual meeting of the Association for Behavior Analysis International Conference, Chicago, IL.