Maria Zulema Cabail

cabailm's picture

Job title: 

Assistant Professor

Phone: 

(516)628-5615

E-mail: 

cabailm@oldwestbury.edu

Building: 

Natural Sciences

Room: 

S-212

Office hours: 

  • Wednesday, 12:30 PM to 2:30 PM.
  • Other times by appointment

Courses taught: 

  • Basic Biological Science I Lab (BS2401) 
  • Basic Biological Science II (BS2410) 
  • Cell Biology (BS4400)
  • Immunology (BS4461)
  • Genetics (BS4460)

Education: 

  • Diploma in Clinical Laboratory Science San Luis, Argentina (2000)
    Universidad Nacional de San Luis (UNSL)
    6 years education, comparable to a master of science
  • Ph. D. in Biochemistry Milwaukee, WI, USA (2006)
    University of Wisconsin-Milwaukee (UWM)
    “Electron Flow Control in Nitrosomonas europaea Hydroxylamine Oxidoreductase”
    Advisor: Prof. A. Andrew Pacheco
  • Advanced Certificate in Clinical Research (CRTP, K30) Stony Brook, NY (2014)
    Stony Brook University (SBU)

Research interests: 

The CABAIL LAB focuses on the field of Immunometabolism and Obesity at the cellular and molecular level. Currently, we are working on two research projects:
a. Pathophysiology Of Obesity-Associated Metabolic Inflammation.
Our goal is to investigate the events involved in the pathophysiology of the chronic low-grade systemic inflammation observed in obese patients. In particular, we are interested in determine the role of autophagy in regulating such inflammatory state.
b. Investigation of the molecular mechanisms underlying the link between obesity and prostate cancer.
The main goal of this project is to elucidate the molecular and cellular mechanisms underlying the association between obesity and prostate cancer risk. This project is being conducted in collaboration with Dr. Manya Mascareno.

Select publications & presentations: 

  • “Auto-thiophosphorylation by Src tyrosine kinase”
    M. Z. Cabail, E.I. Chen, A Koller, and W. Todd Miller
    BMC Biochemistry, 17: 13 (2016) 
  • “The Tyrosine Kinase Domains of the Insulin and IGF1 Receptors Are Functional Dimers in the Activated State ”
    M.Z. Cabail, E. Lemmon, Mark Bowen, Stevan R. Hubbard and W. Todd Miller
    Nature Communications, 6 6406 (2015)
  • “Longevity Surface CD152 (CTLA-4) expression and signaling dictates longevity of CD28null T cells”
    H. Hoff, K. Knieke, M.Z. Cabail, H. Hirseland, G. Vratsanos, G.R. Burmester, G. Jorch, S.G. Nadler, B. Bröker, H. Hebel, M.C. Brunner-Weinzierl
    J. Immunology, 182 5342-5341 (2009)
  • “Quantifying the Photo-induced Release of Nitric Oxide from N,N '-bis-(carboxymethyl)-N,N '-dinitroso- 1,4-phenylenediamine. Effect of Reducing Agents on the Mechanism of the Photo-induced Reactions” 
    M.Z. Cabail, V. Moua, E. Bae, A. Meyer, A.A. Pacheco
    J. Phys. Chem. A, 111 1207-1213 (2007)
  • “Laser photoinitiated nitrosylation of 3-electron reduced Nm europaea hydroxylamine oxidoreductase: Kinetic and thermodynamic properties of the nitrosylated enzyme” 
    M.Z. Cabail, J. Kostera, A.A. Pacheco
    Inorganic Chemistry, 44 225-231 (2005)
  • “Selective -electron reduction of Nitrosomonas europaea hydroxylamine oxidoreductase with NO” 
    M.Z. Cabail, A.A. Pacheco
    Inorganic Chemistry, 42 270-272 (2003)
  • “Kinetic studies of the photoinitiated NO-releasing reactions of N,N '-bis-(carboxymethyl)-N,N '- dinitroso-1,4-phenylenediamine”
    M.Z. Cabail, P.J. Lace, J. Uselding, A.A. Pacheco
    Journal of Photochemistry and Photobiology A-Chemistry, 152 109-121 (2002)